AbstractBackground and Objectives: The risk of cardiovascular disease (CVD) in women has been historically underestimated due to a misperception that females are protected against CVD. There are limited studies of the risk factors and clinical characteristics of female patients presenting with myocardial infarction (MI) in India. To study clinical profile of female patient with MI in India. Methods: We enrolled a cohort of 180 female patients presenting with acute MI between June 2016 to May 2018. Results: The female MI patients were more likely to be dyslipidemic (46.11%), hypertensive (42.22%), obese (40.00%) with high mean BMI (32.05±6.42 kg/m2) and more likely to present with hest pain (83.33%) with STEMI (58.33%) compare to NSTEMI 41.66%). Conclusion: Indian female patients with acute myocardial infarction present at younger age as compared to western women, with chest pain and STEMI is more frequent presentation. Dyslipidemia was the most common associated risk factor followed by hypertension, obesity, and diabetes. Study Design: Cohort Study.