AbstractIntroduction: Infertility is nowadays a global problem affecting couples of reproductive condition. Infertility, prevalent among one in every four couples in the developing countries, is a neglected problem. A significant proportion of women postpone their pregnancy due to education and career to late into the fourth and fifth decades. ART includes in vitro fertilization (IVF) with or without intracytoplasmic sperm injection (ICSI), fresh or frozen embryo transfer, IVF with donor oocytes, intrauterine insemination (IUI) either with ovarian stimulation or in unstimulated cycles. As mother having ART treatment is mostly from higher age group, chronic hypertension and diabetes mellitus may be pre-existing leading to further exaggeration during pregnancy. And if not from higher age group then various factors like endometrial, ovarian, PID, endocrinal problem have significant effect on perinatal outcome and complication. Results: Total number of 193 patients who have taken ART have been included in our study. 51 (48.57%) out of 105 patients had PIH in singleton ART as obstetrical complication which is most common in our study. 41 (46.59%) out of 88 patients had preterm delivery in multiple gestation ART as a most common obstetrical complication in our study. 16 (15.24%) out of 105 patients had Chronic HTN in singleton ART and 14 (15.91%) out of 88 patients had Chronic HTN in multiple gestation ART as maternal complication which is most common in our study. Out of 283 fetus, 41 (14.48%) were IUGR, 9 (3.18%) were fetal anomaly and 17 (6.01%) were IUD. Conclusion: This study helps us to understand that these ART pregnancies are high risk for maternal and fetal complication.