Comparison of Epidural Levobupivacaine 0.125% with Fentanyl 2 mcg/ ml and evobupivacaine 0.125% Alone for Postoperative Pain Management
Olvyna D’souza1, Krishna Patel2, Manish Kokne3
1Professor 2Senior Resident, Department of Anaesthesia, MGM Medical College, Kamothe, Navi Mumbai, Maharashtra 410209, India. 3Assistant Professor, Department of Pharmacology, HBT Medical College, Mumbai, Maharashtra 400056, India.
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Introduction: The aim of the study was to compare effectiveness of single dose epidural 0.125% levobupivacaine with fentanyl 2 mcg/ml and 0.125% levobupivacaine alone in patients undergoing elective lower limb orthopaedic surgery. Methodology: We designed a prospective, randomized, double blind study, in which 60 patients with ASA1 and ASA2 were scheduled to undergo elective lower limb orthopedic surgery. Group A received single epidural block with 8 ml of 0.125% levobupivacaine and Group B received epidural block with 8 ml of 0.125% levobupivacaine and 2 mcg/ml fentanyl. Duration of analgesia, Quality of analgesia, Degree of motor blockade, sedation score, hemodynamic changes and side effects were
assessed. Results: Duration of postoperative analgesia for group B (366±39.70 min) was longer as compared to group A (236±34.99 min). Quality of anaesthesia was significantly better in group B as compared Group A. Conclusion: We conclude that addition of fentanyl 2 mcg/ml to epidural 0.125% levobupivacaine produces significantly better quality and longer duration of postoperative analgesia, good hemodynamic stability and no side effect as compared to 0.125% levobupivacainealone in patient undergoing elective lower limb orthopedic surgeries.
Corresponding Author : Krishna Patel, Senior Resident, Department of Anaesthesia, MGM Medical College, Kamothe, Navi Mumbai, Maharashtra 410209, India.