AbstractBackground and Objectives: Inguinal hernia surgery is one of the commonest day care procedures and have very high incidence of moderate to severe postoperative pain which remains a great challenge for the anesthesiologist to treat it. Multimodal analgesic techniques like parenteral analgesics or regional analgesia are commonly practiced. Peripheral nerve block after surgical closure provide effective postoperative analgesia without any major side effects. This study was designed to compare the analgesic efficacy of Bupivacaine (B) and Ropivacaine (R). Materials and Methods: Fifty adult male patients scheduled for elective inguinal hernia repair were randomly allocated into two groups of 25 each. Group B Bupivacaine, Group R Ropivacaine respectively. General anaesthesia was given. Nerve block was administered at the end of surgery with 15 ml of the study drug. Visual Analog Score (VAS) was noted immediately at the end of surgery and hourly up to 8 hours and the time for rescue analgesia was noted. Independent ‘t’ test, SPSS version 16 was used for analysis. Results: We have found that both the drugs provided excellent postoperative pain relief for inguinal hernia repair with hemodynamic stability. Duration of analgesia was significantly longer in bupivacaine than ropivacaine. (389.96± 25.37mins Vs 301.24±20.72 mins with ‘p’ value < 0.01). Conclusion: At equal concentration, bupivacaine provided prolonged postoperative analgesia than ropivacaine.