Introduction: Alcohol dependence and depression coexist with each other. Now a day’s people use alcohol as a source to relieve their depression.But alcohol dependence increases the harmful effects on the body, also resulting in suicidal tendencies. Aim of the Study: To studythe association between depression and alcohol dependence. Materials and Methods: Adescriptive study was done in the department of Psychiatry at Kamineni Institute of Medical Sciences, L.B. Nagar, Telangana for duration of one year from May 2017 to June 2018. A total of 120 cases who had history of alcohol intake associated with alcoholic dependence and depression were included in the study. SADQ and HAM-D were used to assess severity of alcohol dependence and depression. Results: In the present study, majority of the patients were in the age group of 41-50 years (62.5%). 41.6% (50/120 ) started intake of alcohol at the age of 21-30 years.In the present study there was a male predominance, about 91.6% and females about only 8.3 %. Majority of the patients consumed > 60 gm/24hr of alcohol, i.e., 83.3%(100/ 120). 33.3% (40/120) were married, while 25% (30/ 120) were unmarried and 25% were divorced and 16.6% (20/120) were committed but not married. Depression was seen in all 120 cases. Conclusion: The prevalence of depression among alcohol-dependent persons is high. There is recovery from depression after alcohol detoxification and rehabilitation, and majority of the cases do not necessarily require treatment for the depression. In addition persons that   are depressed have a significantly higher craving for alcohol after detoxification and rehabilitation. It is important to screen for depression and evaluate to determine the treatment needs during detoxification and rehabilitation. 

Keywords: Alcohol Dependence and Depression.