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Indian Journal of Obstetrics and Gynecology

Volume  6, Issue 3, May-June 2018, Pages 282-286
 

Original Article

Comparative Study of the Histopathology on Placenta in Normotensive and Hypertensive Pregnancies

Lambodari P.1, Seal B.N.2, Mukhopadhyay M.3

1Assistant Professor, Department of Gynaecology & Obstetrics, Pt. Jawahar Lal Memorial Govt. Medical College, & Dr. B.R. Ambedakar Memorial Hospital, Raipur, Chhattisgarh 492001, India. 2Professor, Department of Gynaecology & Obstetrics 3Professor, Department of Pathology, Institute of Post-graduate Medical Education & Research S.S.K.M. Hospital, Kolkata, West Bengal 700020, India.

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DOI: DOI: http://dx.doi.org/10.21088/ijog.2321.1636.6318.14

Abstract

Objective: The main objective of the present study to investigate that the histopatological differences in normotensive and hypertensive pregnancies. Research Design: prospective case-control observational study designed was used in current study.

Sample: The present study was conducted in total 200 inpatients in the Department of Gynaecology and Obstetrics, Institute of postgraduate medical education and research with associated S.S.K.M. Hospital Kolkata city in West Bengal, India.

Statistical Analysis: Descriptive, chi-square test and Fisher exact test applied on data analyses.

Result: Finding of the result in current study indicated that the shape of placenta was not found to be statistically significant, commonest mode of cord-insertion was central but it was statistically not significant. The incidence of retro-placental hematoma was increased in the hypertensive group with p-value<0.003, it is highly significant. The incidence ofinfraction was increased in the hypertensive group with pvalue<0.001, it is highly significant. he incidence of calcification was increased in the hypertensive group with p-value<1.000, it is statistically not significant.

Conclusion: The present study concluded that the hypertensive disorders of pregnancy adversely influence the morphology of the placenta. The study reveals that the placental weight and fetal weight are significantly less in hypertensive group than the normotensive group.

Keyword: Histopatological; Normotensive; Hypertensive; Pregnancies.


Corresponding Author : Pratibha Lambodari, Assistant Professor, Department of Gynaecology & Obstetrics, Pt. Jawahar Lal Memorial Govt. Medical College & Dr. B.R. Ambedakar Memorial Hospital, Raipur, Chhattisgarh 492001, India.