Obective: Fine needle aspiration cytology ( FNAC )is less invasive diagnostic modality in almost all lesion with good range of sensitivity, however few false negative and false positive report have been reported, here we emphasis on those misdiagnosed cases with possible explanation. Material & Methods: This study includes a total 43 cases who underwent prior FNAC followed by biopsy examination at our institute. Cytological diagnosis was compared with histological diagnosis. Results: Out of 43 cases studied 26 were benign and 17 were malignant on histology, 3 case of benign and 5 cases of malignant shows discrepancy with histology. We explain possible cause of misdiagnosis.

Keywords: Fine Needle Aspiration; Histological Diagnosis; Salivary Gland; Sensitivity; Specificity.