AbstractIntroduction: Abnormal uterine bleeding is the most common presenting complaint among women of all age groups attending the gynaecology out patient department. Abnormal uterine bleeding is a term used to describe any type of bleeding that does not fall within the normal ranges for amount, frequency, duration and cyclicity. Dysfunctional uterine bleeding is a clinical term used to describe abnormal uterine bleeding not attributable to any underlying organic lesions like Leiomyoma, Inflammation and Polyps. The causes of abnormal uterine bleeding vary with age. The present study was carried out to study the histomorphological spectrum of uterine lesions in women of all age groups presenting with abnormal uterine bleeding and to classify the lesions as Dysfunctional uterine bleeding or Organic causes. Materials and Methods: The retrospective study included a total of 163 specimens received either as endometrial curettings or hysterectomy specimens belonging to all the age groups (reproductive, perimenopausal and post menopausal), presenting with complaints of abnormal uterine bleeding was carried out in the Department of Pathology at a tertiary care centre in rural Haryana. Results: Maximum cases (39.26%) presenting with abnormal uterine bleeding were seen in the age group 31-40 years. Out of total 163 cases, there were 91 (55.82%) DUB cases, 69 (42.33%) were organic lesions and 3 (1.84%) cases were inadequate for opinion. Proliferative phase was seen in maximum cases of dysfunctional uterine bleeding (36/91 cases) and leiomyoma was the commonest pathology in organic lesions category (24/69 cases). Conclusion: Study of histomorphological pattern of the endometrium in patients of all the age groups presenting with abnormal uterine bleeding helps to diagnose and categorize the lesions as Dysfunctional uterine bleeding or Organic causes, to plan specific treatment modality, to assess therapeutic response and to rule out carcinoma.
Keywords: Abnormal Uterine Bleeding; Dysfunctional Uterine Bleeding; Hyperplasia; Leiomyoma; Normal Cyclical Endometrium.