AbstractBrief Introduction: Postpartum Depression is characterized by a depressed mood, excessive anxiety, and insomnia, changes in weight and in severe cases suicidal ideation. Onset is generally within 12 weeks post childbirth. Mothers afflicted with PPD become less responsive to infant needs, are less available to them and find mothering an exasperating task. They might develop negative cognitions of being an unfit mother and hence may withdraw themselves from childcare. Objectives of the Study: 1. to assess the incidence of Post Partum Depression in a Post Natal ward at a General Hospital setting. 2. To study the factors associated with Post Partum Depression in a Post Natal ward at a General Hospital setting. 3. To study the relationship between Post Natal Maternal Attachment and Post Partum Depression. Methodology: The present study is a hospital based cross-sectional study. The sample consists of post partum women at the Post Natal ward, Department of Obstetrics-Gynaecology, Yenepoya Medical College Hospital, Mangalore. A total of 200 patients above the age of 18 years were recruited for the study. Self report measures-Edinburgh Postnatal Depression Scale (EPDS) and The Postpartum Maternal Attachment Scale, were used.The data is analyzed using descriptive statistics. For measuring relationship & association between risk factors and Post Partum Depression, t test is used. Results: In the EPDS postpartum evaluation of depression levels, 6 women (2.5%) showed scores above the cutoff point of 13.The mean age of the study group was 20-30yr. Most of the participants were stay-at-home mothers (n = 174, 87%). Most of the pregnancies were unplanned (62%). Conclusion: The prevalence rate of PPD in a general hospital setting is 2.5%, this study identifies PPD as an important issue in women’s reproductive health. The relationship between insecure attachment style and PPD symptoms, which has been previously shown in western studies, has been confirmed.