Abstract Background: This study was conducted to compare efficiency of plain lidocaine with combination of adjuvant tramadol with lidocaine in intravenous regional anesthesia in terms of onset and duration of sensory and motar blockade. Methods: Sixty patients were divided in to 2 groups; the first group received 0.5% of 40 ml of plain lidocaine and the second group received 0.5% of lidocaine with tramadol 100 mg 40 ml. Preoperative and intraoperative hemodynamic parameters were monitored and recorded at 1,5,10,20,30,40 minutes after anesthesia. Results: The onset time of sensorial block was shorter and duration of sensorial block was longer in group 2 than group 1. The onset of motor blockade and duration of motor blockade was longer in group 2 than group 1. There was no comparatively significant differences in hemodynamic vital parameters in both groups. Conclusions: IVRA with addition of adjuvant tramadol ligocaine is effective and safer than the 0.5% ligocaine.