AbstractIntroduction: Hepatitis is one of the most common communicable diseases leading to permanent damage of the liver causing disability and even death. Health care personals are increasingly faced with the challenge of dealing with these patients on a day-to-day basis. The purpose of the study was to assess the effectiveness of Socratic Method of teaching on knowledge and attitude regarding hepatitis among nursing students. Methods:Data collection was done using demographic proforma; structured knowledge questionnaire and an attitude scale. Results: The analysis revealed that the post test mean scores for knowledge and attitude were significantly higher than the pre test mean scores i.e. the t-value for knowledge was t60=10.09 and for attitude was t60=7.23, which were found to be significant at 0.05% level. This significant improvement in post test scores revealed that there was an improvement in knowledge and attitude of nursing students. Conclusions: Based on the findings it is concluded that the Socratic Method of teaching is highly effective in improving knowledge and attitude regarding hepatitis among nursing students.