Objective: The popliteal vein is the main vein of lower limb, generally accompanied by the popliteal artery in the popliteal fossa.  It is of great  importance  to  have  the  knowledge  of  the veins of the lower limb and their anomalies, so as to avoid any vascular injury during the surgery on lower limb and for improved assessment and treatment of deep vein thrombosis. Hence, retrospectively to review and evaluate the types of variations and their frequencies  seen within the popliteal fossa, we carried out a cadaveric study in the Department of Anatomy of  Dr P.D.M.M.C. Amravati.   Materials and Methods: In the dissection hall, during routine dissection of formalin fixed cadavers of the adult donors a retrospective study of 20 bilateral (40 unilateral) lower limbs was performed.  Results: We found one variation in lower limb vein of a  64 year male cadaver.  In this case, the popliteal vein instead of continuing as femoral vein  bifurcated into  two veins  one of  which separately opened into the femoral vein in  the femoral triangle. Conclusion: Variations in popliteal fossa venous anatomy have many important clinical implications in deep venous thrombosis as well as in lower limb surgery . 

Keywords: Adductor Magnus; Popliteal Vein; Femoral Vein; Profunda Femoris Vein.