Breast carcinoma is emerging as the common most malignancy globally. In India, the rate of cervix cancer is decreasing while breast cancer is on the increase, especially in urban areas. Breast carcinoma continues to be a major health problem despite a decrease in mortality rate over the past 2 decades. The aim of this study is to determine if any correlation exists between estrogen receptor (ER) and progesterone receptor (PR) with respect to age, menopausal status, grade, tumor size and lymph node status in breast carcinoma. A total 50 cases of invasive duct cancers were included in this study. This study was on histopathology of excised specimens of 50 females with breast carcinoma operated by trained doctors. The hormone receptors were assessed immunohistochemically and compared with patient’s age, menopausal status, grade, tumor size and lymph node status of tumor. Correlating the above factors with hormone receptor status, increase positivity of ER/PR in post menopausal age group (66.67%), small tumor size (83.33%), moderately differentiated tumors (76.67%) and negative lymph node status (56.67%) was found. Assessment of hormone receptors for clinical management of breast cancer patients is strongly advocated to provide prognostic information and better therapeutic options.

Keywords: Breast Carcinoma; Estrogen; Progesterone.