Background: Prostate cancer is increasingly becoming one of the most significant health problems facing men and the commonest cause of cancer-related death in men globally. Thus, screening has immense public health importance.

The aim of the study: To determine effectiveness of the educational program on attitudes concerning contributing factors and early detection for prostate cancer.

Methods: Quasi-experimental study design pre-test and post-test for both the study and the control group was used to collect the data from 160 men. Research tool was developed by Myers et al., (2005). Reliability was calculated by Cronbach alpha method and it was 0.84 to explore employee’s attitudes regarding contributing factors and early detection for prostate cancer. Data collection was done in 10th December, 2021 to 10th January, 2022. The data was analyzed and interpreted in terms of objectives and research hypotheses. Analysis was done by using descriptive and inferential statistics.

Results: The highest percentages of employees’ have positive attitudes concerning contributing factors and intention to performing early detection tests for PCA. There are no significant differences between study and control group in pre-test, while there are highly significant differences between study and control group in post-test.

Conclusion: The results study demonstrated effectiveness of the educational program in change behaviour of employees to adopt prostate cancer prevention strategies and intend to participation in early detection screening testing among participants.This study recommends Ministry of health should organize public health campaigns using the mass media to improve attitudes toward prostate cancer and use of screening practices related to diagnosis and prevention of prostate cancer.