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Indian Journal of Ancient Medicine and Yoga

Volume  17, Issue 3, July - Sept. 2024, Pages 125-135
 

Review Article

Modulation of Genetics and Epigenetics Factors in Male Infertility through Yoga-Based Lifestyle Intervention

Piyush Sharma1, Nitin Kumar2, Deepak Kothari

1Assistant Professor,   Department of Zoology, 2Assistant Professor,  Department of Physical Education, Sanatan Dharm
College, Muzaffarnagar 251001, Uttar Pradesh, 3Senior  Consultant, Department of Medicine (Endocrinology),   Maharaja Agrasen Hospital, Punjabi Bagh 110026, New  Delhi, India.
 

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DOI: https://dx.doi.org/10.21088/ijamy.0974.6986.17324.2

Abstract

Male infertility, a complex condition affecting a significant proportion of couples   worldwide, often involves genetic factors such as Y chromosome microdeletion,  mutations in Azoospermia factor (AZF) genes, SRY gene, and Androgen receptor (AR)   gene. These genetic abnormalities can lead to impaired spermatogenesis and resultant   azoospermia or oligospermia. Understanding these genetic factors is crucial for diagnosis  and management of male infertility.  Yoga-based alternative therapies have gained attention for their potential in improving  overall health and well-being, including reproductive health. Studies have suggested
that yoga practices, encompassing physical postures (asanas), breathing techniques   (pranayama), and meditation, can reduce stress, enhance hormonal balance, improve  blood circulation, and modulate immune function. These benefits may contribute to
ameliorating underlying causes of male infertility associated with genetic mutations.  This review explores the role of Y chromosome microdeletion, AZF gene mutation,  SRY gene mutation, and AR gene mutation in male infertility and reviews the potential
of yoga-based alternative therapies in mitigating these genetic factors. Further research  and clinical trials are warranted to validate the efficacy of yoga as a complementary  approach to conventional treatments for male infertility.
 


Keywords : Azoospermia factor; AZF mutation; cytogenetic; Male infertility; Y chromosome microdeletion; SRY gene mutation; Yoga.
Corresponding Author : Piyush Sharma,