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Indian Journal of Emergency Medicine

Volume  10, Issue 3, July - Sept. 2024, Pages 119-123
 

Original Article

Clinical Profile of Dengue Fever Patient with Thrombocytopenia less than one lakh/Cumm among Adults in Ed

Snehith C Patil1, C.A Bopanna2, Harold Maxim Lewis3, Kiran Tatti4, Kevin Koshy Joseph5, Shankarachari S M6

1,4,5Postgraduate, 2Assistant Professor,   3Professor & HOD, 6Junior Resident, Department of Emergency
Medicine, KVG Medical College & Hospital Kurunjibag, Sullia  574327, Karnataka, India.
 

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DOI: http://dx.doi.org/10.21088/ijem.2395.311X.10324.2

Abstract

Dengue infection presents varied clinical manifestation ranging from asymptomatic or    simple viral illness to circulatory shock (DSS), severe bleeding and death. So, early diagnosis   and recognition of complication is a cornerstone in management. It is prospective observational   study which was conducted in KVG medical college. With inclusion of 100 cases all seropositive
for dengue antigen or antibodies or both and platelet count less than 1lakh/cumm. Done     from October 2022 till September 2023. Chi square test was used for data analysis. The study  was mainly focused on bleeding manifestations, to find correlation between platelet count  and bleeding manifestations. Routine investigations that include CBC with ESR, RUE, ECG,  Dengue serology (NS1, IgM, IgG), RFT, LFT, serum electrolytes. Coagulation profile was done  in suspected DHF patients. Leucopoeniais taken below 4000 cells/cumm. Out of 100 patients,  88 were classified under dengue fever with/without haemorrhage and rest 12 were classified
into Dengue haemorrhagic fever as per WHO criteria. The presenting symptoms were: fever   (97%), headache (78%), retro orbital pain (32%), myalgia (72%), arthralgia (52%), nausea (62%),  vomiting (39%), abdominal pain (56%),diarrhoea (15.2%), bleeding manifestations (42%). The   major physical findings noted included positive tourniquet test (21%), hepatomegaly (15%),  bradycardia (18%), pleural effusion (6%) and ascites (11%). The study concluded that there was  no association between bleeding manifestation and platelet counties bleeding can happen at  any level of platelets count. Hence prognostication based on platelet count can’t be done.
 


Keywords : Dengue fever; Thrombocytopenia; Dengue Hemorrhagic fever; Bleeding manifestations.
Corresponding Author : C.A Bopanna