Flaps are important in covering defects caused by trauma, tumour excision, lower limb vascular ulcer, or diabetes mellitus. Distal flap necrosis is one of the most common postoperative complications for flaps, leading to increased morbidity, prolonged hospital stay and need for repeat surgery.Pentoxifylline (PTXF) is a vasoactive agent that improves the flow of blood by reducing its viscosity. In our patient, we studied the usefulness of pentoxifyllineas an adjuvant to prevent flap necrosis.