AbstractBacteria Colonized wound become a major problem in wound management. Infections may lead to delayed healing process or severe complications. Thus, the incorporation of antimicrobial agents such as silver, iodine, etc., into the dressing material provides protection against microbes. One of the element available in market is Dimethyl tetradecyl [3-(trimethoxysily l) propy l] ammonium chloride (DTAC) based 3D-hydrocellular wound dressings have emerged. In this article we highlight the roleof DTAC based 3D-hydrocellular microbicidal wound dressing.