AbstractSurgical site infection (SSI) is defined as an infection that occurs in the part of the body where the surgery is done. It can be superficial, deep, and organ/space SSI. Surgical site infections lead to increased morbidity, mortality, length of stay, and cost of money each year. Our skin is a natural barrier against infection, and any surgery which causes breakage in the skin may lead to an infection. The chances of developing surgical site infection are 1% to 3% if you have surgery. Most SSIs can be treated with antibiotics, and sometimes additional procedures or surgery may be needed to treat them. Surgical site infection (SSI) usually occurs within 30 days after surgery if there is no implant or within 1 year if the implant is placed and involves any part of the anatomy other than the incision which was opened or manipulated during the surgery. There is a chance for SSI for the patient who is hospitalized 7 days longer, is 55% more likely to spend time in ICU, and is times more likely to be re-admitted.