AbstractIntroduction: Wolff–Parkinson-White syndrome (WPW) is an uncommon cardiac disorder where there is an abnormal band of atrial tissue that connects atria and ventricles. Continuous spinal anesthesia is preferred to avoid multidrug administration and stimulus due to laryngoscopy. Case Report: A 47 yrs old female, known case of WPW syndrome was posted for hysterectomy. Pre-anesthetic evaluation was done. A 12 lead ECG was done which showed left axis deviation, short PR interval and delta waves. The 2D – Echo showed thickened MV leaflets with grade-1 MR with normal LV systolic function and EF of 60%. The case was planned to be taken under continuous spinal anesthesia. The Anti-Arrhythmic drugs and Defibrillator were kept ready. Intermittent boluses of Inj. Bupivacaine (H) 0.5% was given through catheter to achieve sensory and motor blockade. Inj. Fentanyl 25mcg was given at the end of the procedure as analgesic dose. Intra operative vitals were stable. Postoperative period was uneventful. Conclusion: Patient with WPW Syndrome can be managed successfully by continuous spinal anesthesia technique which uses low dose of anesthetic helps in maintaining cardiovascular stability intraoperatively and duration can be extended if surgery is prolonged. Keywords: Continuous Spinal Anesthesia, WPW Syndrome, Ventricular Tachycardia. Key Messages: Hemodynamic changes can occur with WPW syndrome with arrhythmias. This can be avoided with definitive treatment like Radiofrequency ablation. Our patient came with WPW Syndrome with stable hemodynamics so continuous spinal anesthesia can offer stable hemodynamics with minimum use of local anesthetics. We are reporting a case of WPW Syndrome with successful anesthetic management