AbstractIntroduction: Breast cancer is one of the leading causes of death among females. This necessitates a proper screening modality for early diagnosis and treatment of breast cancer. Due to limited resources in few setups it would be difficult to get an access to mammography. Hence in our study we are trying to evaluate the diagnostic accuracy of ultrasonography to use it as an alternative to mammography in breast cancer patients. Materials and Methods: A prospective study was conducted on 80 women presenting with breast condition. All patients underwent sonomammography followed by histopathological assessment of the lump. Results: Irregular shape with irregular margins on sonomammography was found to be significant marker of malignancy with extensive vascularity. Calcification in malignancy was 7.92 times more common than benign. The diagnostic accuracy of sonomammography was 75% with sensitivity and specificity of 72.58% and 83.33% respectively. Conclusion: Our study concluded that sonomammography can be used as a diagnostic modality for breast conditions in resource limited facilities. Keywords: Breast Cancer; Sonomammography; Benign lesion of breast; Diagnostic accuracy of sonomammography; BIRADS.