ntroduction: Nosocomial pneumonia associated with mechanical ventilation (due to endotracheal tube or tracheostomy) develops within 48 hrs. or more than 48 hrs. Epidemiology: VAP occurs in 10- 65% of all ventilated cases, Hospital-acquired pneumonia (HAP)is the second most common hospital infection., 90% of all nosocomial infections occurring in ventilated patients are types of pneumonia. The Indian study indicates the incidence of VAP is 57.14% and the incidence density of VAP was 31.7/1000 ventilator days, another study indicates the VAP rate was 6.242/ 1000 ventilator days. The mortality rate ranged from 16.2% to 74.17%. The highest mortality rate was reported from a study in India. Pathogens: Staphylococcus aureus (44%) are the most frequently isolated microbes. Acinetobacter baumanii (30%), Pseudomonas aeruginosa (12%), Stenotrophomonas maltophilia (7%), Klebsiella pneumoniae (6%), and Serratia marcescens (2%) were isolated from the transtracheal aspirates or bronchoalveolar lavage in patients with VAP. Types of pneumonia: Community-acquired pneumonia, Hospital-acquired pneumonia, and Ventilator-associated pneumonia Common signs and symptoms are Difficulties in breathing, Tachycardia Fever, Sweating, Shivering, Loss of appetite, Pain in the chest, Hemoptysis, Headache, Fatigue, Nausea, Vomiting Complications: Septicemia, Lung abscess, Acute respiratory distress syndrome (ARDS), Middle ear infection, Blood infection, Meningitis, Sepsis, Pericarditis, Atelectasis, Pleural effusion, Hypotension, Tachypnea, Confusion, Septic shock, Decreases in breath sounds, and Unequal chest expansion. Conclusion: Nurses play a key role in the intensive care unit, they need to know about VAP, they have to Conduct a Physical examination of the patient and clinical pulmonary infection score (CIPS) to be recorded. they Check vital signs (Temperature, Pulse, Respiration, Blood pressure, and oxygen saturation. Assist the intensivist in the assessment of Progression of infiltrate. They are responsible for the Management of a patient with pneumonia by providing quality nursing care.