Introduction: The most important consideration in evaluating patients with solitary thyroid nodule is whether the nodule is a thyroid carcinoma or not. Solitary thyroid nodule can be both neoplatic or non neoplastic. Histological examination helps in the final diagnosis and also to know the frequency of occurrence of various histological varieties in solitary thyroid nodules. Aim: Our study was aimed to evaluate the solitary thyroid nodules histologically and categorise them according to their histomorphology findings. Materials and Methods: A total of 68 cases of solitary thyroid nodules were studied over a period of 4yrs and histopathology findings were recorded. Results: 68 cases of solitary thyroid nodules were studied for a period of 4yrs. The sex distribution of solitary thyroid nodules showed female preponderance. Mean age of presentation was 48yrs. Among 68 cases 38 were non neoplastic and 30 were neoplastic. Among non neoplastic, 20 were colloid noules/colloid cyst, 16 were hyperplastic nodules of nodular goiter and 2 were hashimotosthyroidits. Among 30 neoplastic, 20 were follicular adenoma, 5 were follicular carcinoma, 3 were papillary carcinoma and 2 were follicular variant of papillary carcinoma. Conclusion: To conclude, the most common lesion of solitary thyroid nodule in our study was non neoplastic lesion. Preoperative evaluation helps us to minimize the extent of surgery and hence morbidity.

Keywords: Colloid nodule of thyroid; Hashimotos thyroiditis; Histopathology; Papillary carcinoma thyroid; Solitary thyroid nodule.