Emotional blunting, alogia, avolition, a sociality and anhedonia are features of negative symptoms. Negative symptoms are blamed for poor outcome and persistent disability in schizophrenia. The high hopes of cure of negative symptoms by SGAs have been belied. Due to the complex nature of negative symptoms, several methodological issues are raised and it is treated with different antipsychotics and novel agents with varied results. The development of innovative treatment and increased collaboration is needed to overcome the current limitation. Keywords: Negative Symptoms; First Generation Antipsychotics; Second Generation Antipsychotics.