Introduction: An Autopsy doesn’t always yield cause of death easily. In 20-25% cases detailed
history, visit to scene of incident, histological, toxicological& microbiological investigations
might be required. Even then circumstantial evidence plays important role.
Case Reports: Article presents and discusses four cases, two of electrocution, one natural neonatal death and one accidental phosphorous poisoning. How challenging it can be to ascertain cause of death at rural hospital set up.

Discussion: Various natural and unnatural causes can lead to death without any evident pathology or signs such as sudden infant deaths, biochemical disturbances, functional disorders like epilepsy, electrocution, concealed trauma, certain poisonings, vagal and anaphylactic shocks.

Conclusion & Recommendations: All necessary and possible investigations should be done in obscure deaths to exclude such causes and to prevent allegations that the death was not investigated as fully as it should have been. Special efforts are needed to raise awareness regarding use and storage of hazardous materials to prevent accidental deaths.