Population explosion has posed a serious threat to the progress and survival of mankind. The Oral contraceptive pills (OCPs) quickly have become the most effective, acceptable and reversible contraceptive. OCPs contain an estrogen and progesterone. Serious side effects of OCPS are cardiovascular diseases such as myocardial infarction, thrombosis, cerebral hemorrhage, and arteriosclerosis. Many epidemiological studies have clearly indicated that arteriosclerosis and myocardial infarction are closely linked to an impaired lipid and lipoprotein metabolism and from such studies it’s also documented that treatment of the lipoproteinemia will reduce the risk of coronary heart disease.

Keywords: Oral Contraceptive Pills (OCPs), High Density Lipoprotein Cholesterol (HDL); Low Density Lipoprotein Cholesterol (LDL); Total Cholesterol (TC) and Triglycerides (TG).