AbstractBackground: Study of lipid profile in young smokers provides opportunity to explain the physiological consequences of the cigarette smoking activity. Cigarette smoking is the second cause of death in the world. The addictive liability and pharmacological effects of smoking are primarily mediated by the major tobacco alkaloid nicotine. Cigarette smoke may promote atherogenesis by producing oxygenderived free radicals that damage lipids. Cigarette smoking is associated with impaired endotheliumdependent vasodilatation and cardiovascular disease (CVD). As the current report concerns solely to the study of lipid profile in normal healthy controls and smoking male subjects, the results of this study can be correlated with other biochemical, physiological and clinical aspects. Aim: The Aim of our study was to determine and compare lipid profile in smokers and nonsmokers. Method: A Total No. of 100 subjects were selected, out of which 50 were healthy individual and 50 were young smokers less than 35 years of age. The lipid parameter were analyzed using kits on automated biochemistry analyzer. Result: The levels of total cholesterol, Triglyceride, LDLC and VLDLC were significantly higher while the level of HDL was significantly lower in smokers as compared to their levels in non smokers.
Keywords: Lipid Profile; Smokers; NonSmokers.