AbstractUse of silicone derivative and onion extract had been reported in the prevention of abnormal scarring. Our study showed the preventive use of silicone derivative plus onion extract gel on abnormal scars after scald burns. Next to silicone based products, onion extract or cepalin has been highlighted as one potential anti-scarring agent over recent years. Based on several studies, onion extract alone or in combination with allantoin and heparin seems to alleviate the wound healing process and appears beneficial for preventional application in fresh scars. During each visit, pain and itching scores were graded by the patients and scar characteristics were observed by surgeons using the Vancouver scar scale (Table 1). Pain and itch score values from patients' who applied silicone derivative plus onion extract gel. No adverse events were reported by any of the patients. A silicone derivative plus onion extract gel is safe and effective for the preventing the abnormal scarring after scald burn injury.