AbstractFibromas are benign growths of fibrous, connective tissue. Gingiva is a common site of oral fibromas. Owing to similar and overlapping presentation of various oral lesions, arriving at a specific diagnosis becomes difficult. Lesions like pyogenic granuloma, irritational fibroma, Peripheral Ossifying Fibroma (POF) and Angio-granuloma are more or less indistinguishable. POF is a relatively rare gingival lesion with multiple histopathologic presentations. The pathogenesis of POF is not amply clear though it is considered reactive in nature. Etiological stimulus may be irritation from dental calculus, plaque, orthodontic appliances or faulty restorations. A clinical report of a 67 year old male with a large peripheral ossifying fibroma in the anterior maxilla showing profuse growth resulting in facial asymmetry and causing masticatory discomfort, is presented. Surgical excision of the lesion was done and subsequent histopathologic confirmation of excised sample confirmed the clinical diagnosis.