Craniosacral therapy (CST) was founded as an ancient manual therapy technique to evaluate and treat altered static and dynamic skull bone mobility in relation to sacrum during respiration. Although neurophysiological basis for pediatric neurodevelopmental disorders (PND) is clear, there is still paucity in evidence on cranial mechanical aspects in these disorders. This critical review was aimed to provide an update on the literature by synthesizing evidence for CST in PND. Limited but convincing evidence suggested the application of CST in children and adolescents with attention-deficit hyperactivity disorder, and in few developmentally delayed newborns. There is need for more studies and high quality clinical trials in this area.

Keywords: Craniosacral therapy; Manual therapy; Pediatric neurodevelopmental disorders.