Problem Statement: “A study to assess the effectiveness of structured teaching program on the knowledge of caregivers of schizophrenic patients in Psychiatric ward, New Civil Hospital, Surat.” Objectives • To assess the knowledge of caregivers of schizophrenic patients. • To implement a structured teaching program to the caregivers regarding schizophrenia. • To assess the effectiveness of a structured teaching program on caregivers of schizophrenic patients. • To correlate the demographic data of the caregivers of schizophrenic patients to Post test knowledgescore. Methodology: The research design is pre experimental one group pre test post test design; research setting selected was Psychiatric Ward, New Civil Hospital, Surat, 30 caregivers of schizophrenic patients were selected as sample. Structured questionnaire was used as tool for data collection, lesson plan was prepared which was used as intervention. Pre test was conducted and structured teaching program was administered and after a time of 7 days post test was done to assess the effectiveness of structured teaching program. Data Analysis: Collected data was presented and analysed in both descriptive and inferential statistics. Pre - test and post test results were assessed, then demographic variables were correlated with the post - test knowledge score. Results: The mean post test knowledge score was higher than mean pre - test knowledge score with the mean difference of 5.1 which was statistically proved and it revealed that the structured teaching program was effective. The calculated ‘t’ was greater than tabulated ' t ' and so the investigator concluded that there was significant increase in the mean post - test knowledge score as compared to the mean pre - test knowledge score after the administration of the structured teaching program . The calculated chi - square value was greater than tabulated value for selected demographic variables which proved that there was significant relationship between selected demographic variables and mean post test result. Conclusion: Knowledge deficit existed in all the caregivers of Schizophrenic patients regarding Schizophrenia admitted in Psychiatric ward of New Civil Hospital, Surat. The Structured teaching program was found to be effective in enhancing the knowledge of samples regarding Schizophrenia. Samples gained significant knowledge and enhance the skill after expose to Structured Teaching Program. There is significant relationship between selected demographic variables and the post test knowledgescore. Keywords: Schizophrenic patients; New Civil Hospital; Research design; Deficit existed