AbstractIntroduction: Ovarian tumors are a group of diverse neoplasms with a varied clinical, morphological and histological feature. The varied anatomy, histogenesis and its peculiar physiology including the cyclical changes from puberty to menopause give rise to number of cell types, each of which may give rise to tumors. Materials and methods: A 3-year retrospective study of histologically proven ovarian neoplasms where the tumors were classified according to World Health Organization (WHO) 2014 classification and their clinical and histopathologic parameters were analyzed. Results: Of all 138 ovarian tumors studied, 94 (68.12%) were benign, 13 (9.42%) borderline and 31 (22.5%) were malignant in nature. Benign tumors chiefly presented with abdominal pain with median age of 39. Mature cystic teratoma was found to be the most common benign tumor. Borderline tumors presented at a median age of 37. Borderline serous and mucinous tumors (30.76%) were the most common borderline tumors. Malignant tumors presented frequently with abdominal mass and at median age of 48. According to WHO classification of tumors based on cell of origin, surface epithelial tumor were the most common ovarian neoplasms, accounting for 63.04% cases, followed by germ cell tumor (24%) and sex-cord stromal tumors (8.7%). Conclusion: Surface epithelial tumors were the most common histopathological subtype of ovarian tumors. Benign and borderline tumors were predominantly found in reproductive age, whereas malignant tumors were seen in perimenopausal and postmenopausal women. Since the prognosis, therapeutic strategies including multidisciplinary approach depend primarily on the histopathologic diagnosis, an accurate pathological evaluation and classification is of prime importance. The multidisciplinary approach employed has its own medico legal implications.
Keywords: Neoplasm; Epithelial Cancer; Ovarian